The city of Lisbon is rich in architecture; Romanesque, Gothic, Manueline, Baroque, Traditional Portuguese, Modern and Post-Modern constructions can be found all over the city. The city is also crossed by great boulevards and monuments along these main thoroughfares, particularly in the upper districts; notable among these are the Avenida da Liberdade (Liberty Avenue), Avenida Fontes Pereira de Melo, Avenida Almirante Reis and Avenida da República (Republic Avenue). The most famous museums in Lisbon are the Museu Nacional de Arte Antiga (National Museum of Ancient Art), the Museu do Azulejo (Museum of Portuguese-style Tile Mosaics), the Museu Calouste Gulbenkian (Calouste Gulbenkian Museum, containing varied collections of ancient and modern art), the Lisbon Oceanarium (Oceanário de Lisboa, the second largest in the world), the Museu Nacional do Traje e da Moda (National Museum of Costume and Fashion), the Berardo Collection Museum (Modern Art) at the Belém Cultural Center, the Museu Nacional dos Coches (National Coach Museum, containing the largest collection of royal coaches in the world), the Museu da Farmácia (Pharmacy Museum) and the Museum of the Orient.

Lisbon's opera house, the Teatro Nacional de São Carlos, hosts a relatively active cultural agenda, mainly in autumn and winter. Other important theatres and musical houses are the Centro Cultural de Belém, the Teatro Nacional D. Maria II and the Gulbenkian Foundation.